Takeshi Kamiya's (Masaki Okada) father Tsukasa (Takeshi Kaga) is a doctor at a major hospital. Takeshi also wants to become a doctor, but he keeps failing his medical school entrance exams. Takeshi becomes frustrated and leaves home. He begins to work as a nurse at a hospital. Takeshi takes care of Joe Tobita (Akira Terao), who has been comatose for the past 45 years. One day, while Takeshi takes care of Joe, he miraculously wakes up.
Even though Joe is now an elderly man, his mental age is still that of a 19-year-old when he got in an accident. Joe gets better slowly. Meanwhile, Joe doesn't have family to pay for his hospital bills and his bills are paid for by the major hospital where Takeshi's father works. The hospital pays for Joe's bills on the condition that he becomes a subject of their medical research. Joe is soon set to transfer to another hospital. Takeshi and Joe have become close friends and in order to take Joe's youth back, Takeshi takes Joe out of the hospital on a road trip. The travels of a 64-year-old troubled kid Joe and 27-year-old Takeshi begins.